Direct Demonstration That Loop1 of Scap Binds to Loop7: A CRUCIAL EVENT IN CHOLESTEROL HOMEOSTASIS

Cholesterol homeostasis is mediated by Scap, a polytopic endoplasmic reticulum (ER) protein that transports sterol regulatory element-binding proteins from the ER to Golgi, where they are processed to forms that activate cholesterol synthesis. Scap has eight transmembrane helices and two large lumin...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Zhang, Yinxin, Lee, Kwang Min, Kinch, Lisa N., Clark, Lindsay, Grishin, Nick V., Rosenbaum, Daniel M., Brown, Michael S., Goldstein, Joseph L., Radhakrishnan, Arun
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Membrane Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933461/
https://ncbi.nlm.nih.gov/pubmed/27068746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729798
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires