Direct Demonstration That Loop1 of Scap Binds to Loop7: A CRUCIAL EVENT IN CHOLESTEROL HOMEOSTASIS

Cholesterol homeostasis is mediated by Scap, a polytopic endoplasmic reticulum (ER) protein that transports sterol regulatory element-binding proteins from the ER to Golgi, where they are processed to forms that activate cholesterol synthesis. Scap has eight transmembrane helices and two large lumin...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Zhang, Yinxin, Lee, Kwang Min, Kinch, Lisa N., Clark, Lindsay, Grishin, Nick V., Rosenbaum, Daniel M., Brown, Michael S., Goldstein, Joseph L., Radhakrishnan, Arun
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Membrane Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933461/
https://ncbi.nlm.nih.gov/pubmed/27068746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729798
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы