טוען...
Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis
When human fibroblasts take up plasma low density lipoprotein (LDL), its cholesterol is liberated in lysosomes and eventually reaches the endoplasmic reticulum (ER) where it inhibits cholesterol synthesis by blocking activation of SREBPs. This feedback protects against cholesterol overaccumulation i...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086274/ https://ncbi.nlm.nih.gov/pubmed/24920391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02882 |
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