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Mechanistic Insights into the Cholesterol-dependent Binding of Perfringolysin O-based Probes and Cell Membranes

Cholesterol distribution in the cell is maintained by both vesicular and non-vesicular sterol transport. Non-vesicular transport is mediated by the interaction of membrane-embedded cholesterol and water-soluble proteins. Small changes to the lipid composition of the membrane that do not change the t...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Johnson, Benjamin B., Breña, Mariana, Anguita, Juan, Heuck, Alejandro P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653841/
https://ncbi.nlm.nih.gov/pubmed/29061991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14002-x
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