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Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain (ASC)

Activation of caspase-1 is essential for the maturation and release of interleukin (IL)-1β and IL-18, and occurs in multi-protein complexes, referred to as inflammasomes. The apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is the essential adaptor protein for re...

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Библиографические подробности
Главные авторы: Bryan, Nicole B., Dorfleutner, Andrea, Rojanasakul, Yon, Stehlik, Christian
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652671/
https://ncbi.nlm.nih.gov/pubmed/19234215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802367
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