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Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain (ASC)
Activation of caspase-1 is essential for the maturation and release of interleukin (IL)-1β and IL-18, and occurs in multi-protein complexes, referred to as inflammasomes. The apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is the essential adaptor protein for re...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2652671/ https://ncbi.nlm.nih.gov/pubmed/19234215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802367 |
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