Peroxisome Deficiency Causes a Complex Phenotype because of Hepatic SREBP/Insig Dysregulation Associated with Endoplasmic Reticulum Stress

Regulation of hepatic cholesterol biosynthesis, lipogenesis, and insulin signaling intersect at the transcriptional level by control of SREBP and Insig genes. We previously demonstrated that peroxisome-deficient PEX2(-)(/)(-) mice activate SREBP-2 pathways but are unable to maintain normal cholester...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kovacs, Werner J., Tape, Khanichi N., Shackelford, Janis E., Wikander, Thomas M., Richards, Michael J., Fliesler, Steven J., Krisans, Skaidrite K., Faust, Phyllis L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652311/
https://ncbi.nlm.nih.gov/pubmed/19110480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809064200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados