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Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression

Ketohexokinase (KHK) is the first and rate-limiting enzyme of fructose metabolism. Expression of the two alternatively spliced KHK isoforms, KHK-A and KHK-C, is tissue-specific and KHK-C is predominantly expressed in liver, kidney and intestine and responsible for the fructose-catabolizing function....

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Eberhart, Tanja, Schönenberger, Miriam J., Walter, Katharina M., Charles, Khanichi N., Faust, Phyllis L., Kovacs, Werner J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360681/
https://ncbi.nlm.nih.gov/pubmed/32733884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00566
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