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Disturbed Cholesterol Homeostasis in a Peroxisome-Deficient PEX2 Knockout Mouse Model
We evaluated the major pathways of cholesterol regulation in the peroxisome-deficient PEX2(−/−) mouse, a model for Zellweger syndrome. Zellweger syndrome is a lethal inherited disorder characterized by severe defects in peroxisome biogenesis and peroxisomal protein import. Compared with wild-type mi...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC303355/ https://ncbi.nlm.nih.gov/pubmed/14673138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.1-13.2004 |
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