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Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis

Cholesterol biosynthesis is a multi-step process involving several subcellular compartments, including peroxisomes. Cells adjust their sterol content by both transcriptional and post-transcriptional feedback regulation, for which sterol regulatory element-binding proteins (SREBPs) are essential; suc...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Charles, Khanichi N., Shackelford, Janis E., Faust, Phyllis L., Fliesler, Steven J., Stangl, Herbert, Kovacs, Werner J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677142/
https://ncbi.nlm.nih.gov/pubmed/33240873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.560266
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