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Lactimidomycin, Iso-migrastatin and Related Glutarimide-containing 12-membered Macrolides are Extremely Potent Inhibitors of Cell Migration

Migrastatin (1), iso-migrastatin (5) and lactimidomycin (7) are all glutarimide-containing polyketides known for their unique structures and cytotoxic activities against human cancer cell lines. Migrastatin, a strong inhibitor of tumor cell migration, has been an important lead in the development of...

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書誌詳細
主要な著者: Ju, Jianhua, Rajski, Scott R., Lim, Si-Kyu, Seo, Jeong-Woo, Peters, Noël R., Hoffmann, F. Michael, Shen, Ben
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651819/
https://ncbi.nlm.nih.gov/pubmed/19132897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja808462p
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