Pyrrolysyl-tRNA synthetase:tRNA(Pyl) structure reveals the molecular basis of orthogonality

Pyrrolysine (Pyl), the 22(nd) natural amino acid, is genetically encoded by UAG and inserted into proteins by the unique suppressor tRNA(Pyl)1. The Methanosarcinaceae produce Pyl and express Pyl-containing methyltransferases that allow growth on methylamines2. Homologous methyltransferases and the P...

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Detaylı Bibliyografya
Asıl Yazarlar: Nozawa, Kayo, O’Donoghue, Patrick, Gundllapalli, Sarath, Araiso, Yuhei, Ishitani, Ryuichiro, Umehara, Takuya, Soll, Dieter, Nureki, Osamu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648862/
https://ncbi.nlm.nih.gov/pubmed/19118381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07611
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