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Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation
Pyrrolysine (Pyl), the 22nd natural amino acid and genetically encoded by UAG, becomes attached to its cognate tRNA by pyrrolysyl-tRNA synthetase (PylRS). We have determined three crystal structures of the Methanosarcina mazei PylRS complexed with either AMP–PNP, Pyl–AMP plus pyrophosphate, or the P...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040888/ https://ncbi.nlm.nih.gov/pubmed/17592110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704769104 |
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