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Aminoacylation of tRNA 2′- or 3′-hydroxyl by phosphoseryl- and pyrrolysyl-tRNA synthetases

Class I and II aminoacyl-tRNA synthetases (AARSs) attach amino acids to the 2′- and 3′-OH of the tRNA terminal adenosine, respectively. One exception is phenylalanyl-tRNA synthetase (PheRS), which belongs to Class II but attaches phenylalanine to the 2′-OH. Here we show that two Class II AARSs, O-ph...

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Detalhes bibliográficos
Main Authors: Englert, Markus, Gundapalli, Sharath, Hohn, Michael, Ling, Jiqiang, O'Donoghue, Patrick, Söll, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830498/
https://ncbi.nlm.nih.gov/pubmed/24021645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.08.037
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