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Pyrrolysyl-tRNA synthetase variants reveal ancestral aminoacylation function
Pyrrolysyl-tRNA synthetase (PylRS) is a class IIc aminoacyl-tRNA synthetase that is related to phenylalanyl-tRNA synthetase (PheRS). Genetic selection provided PylRS variants with a broad range of specificity for diverse non-canonical amino acids (ncAAs). One variant is a specific phenylalanine-inco...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778162/ https://ncbi.nlm.nih.gov/pubmed/23994531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.08.018 |
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