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Pyrrolysyl-tRNA synthetase, an aminoacyl-tRNA synthetase for genetic code expansion

Genetic code expansion (GCE) has become a central topic of synthetic biology. GCE relies on engineered aminoacyl-tRNA synthetases (aaRSs) and a cognate tRNA species to allow codon reassignment by co-translational insertion of non-canonical amino acids (ncAAs) into proteins. Introduction of such amin...

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Pubblicato in:Croat Chem Acta
Autori principali: Crnković, Ana, Suzuki, Tateki, Söll, Dieter, Reynolds, Noah M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321558/
https://ncbi.nlm.nih.gov/pubmed/28239189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5562/cca2825
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