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The central role of tRNA in genetic code expansion

BACKGROUND: The development of orthogonal translation systems (OTSs) for genetic code expansion (GCE) has allowed for the incorporation of a diverse array of non-canonical amino acids (ncAA) into proteins. Transfer RNA, the central molecule in the translation of the genetic message into proteins, pl...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Reynolds, Noah M., Vargas-Rodriguez, Oscar, Söll, Dieter, Crnković, Ana
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603357/
https://ncbi.nlm.nih.gov/pubmed/28323071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.03.012
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