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Plasticity and Constraints of tRNA Aminoacylation Define Directed Evolution of Aminoacyl-tRNA Synthetases

Genetic incorporation of noncanonical amino acids (ncAAs) has become a powerful tool to enhance existing functions or introduce new ones into proteins through expanded chemistry. This technology relies on the process of nonsense suppression, which is made possible by directing aminoacyl-tRNA synthet...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Crnković, Ana, Vargas-Rodriguez, Oscar, Söll, Dieter
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540133/
https://ncbi.nlm.nih.gov/pubmed/31075874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092294
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