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Plasticity and Constraints of tRNA Aminoacylation Define Directed Evolution of Aminoacyl-tRNA Synthetases

Genetic incorporation of noncanonical amino acids (ncAAs) has become a powerful tool to enhance existing functions or introduce new ones into proteins through expanded chemistry. This technology relies on the process of nonsense suppression, which is made possible by directing aminoacyl-tRNA synthet...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Crnković, Ana, Vargas-Rodriguez, Oscar, Söll, Dieter
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540133/
https://ncbi.nlm.nih.gov/pubmed/31075874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092294
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