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Engineering aminoacyl-tRNA synthetases for use in synthetic biology

Within the broad field of synthetic biology, genetic code expansion (GCE) techniques enable creation of proteins with an expanded set of amino acids. This may be invaluable for applications in therapeutics, bioremediation, and biocatalysis. Central to GCE are aminoacyl-tRNA synthetases (aaRSs) as th...

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Détails bibliographiques
Publié dans:Enzymes
Auteurs principaux: Krahn, Natalie, Tharp, Jeffery M., Crnković, Ana, Söll, Dieter
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086897/
https://ncbi.nlm.nih.gov/pubmed/33837709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.enz.2020.06.004
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