Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNA(Gln) formation

The molecular basis of the genetic code relies on the specific ligation of amino acids to their cognate tRNA molecules. However, two pathways exist for the formation of Gln-tRNA(Gln). The evolutionarily older indirect route utilizes a non-discriminating glutamyl-tRNA synthetase (ND-GluRS) that can f...

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Autores principales: Nureki, Osamu, O’Donoghue, Patrick, Watanabe, Nobuhisa, Ohmori, Atsuhiko, Oshikane, Hiroyuki, Araiso, Yuhei, Sheppard, Kelly, Söll, Dieter, Ishitani, Ryuichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978374/
https://ncbi.nlm.nih.gov/pubmed/20601684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq605
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