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Rational design of an evolutionary precursor of glutaminyl-tRNA synthetase
The specificity of most aminoacyl-tRNA synthetases for an amino acid and cognate tRNA pair evolved before the divergence of the three domains of life. Glutaminyl-tRNA synthetase (GlnRS) evolved later and is derived from the archaeal-type nondiscriminating glutamyl-tRNA synthetase (GluRS), an enzyme...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251134/ https://ncbi.nlm.nih.gov/pubmed/22158897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117294108 |
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