C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNA(Sec)

O-Phosphoseryl-tRNA kinase (PSTK) is the key enzyme in recruiting selenocysteine (Sec) to the genetic code of archaea and eukaryotes. The enzyme phosphorylates Ser-tRNA(Sec) to produce O-phosphoseryl-tRNA(Sec) (Sep-tRNA(Sec)) that is then converted to Sec-tRNA(Sec) by Sep-tRNA:Sec-tRNA synthase. Ear...

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Detalhes bibliográficos
Main Authors: Sherrer, R. Lynn, Araiso, Yuhei, Aldag, Caroline, Ishitani, Ryuichiro, Ho, Joanne M. L., Söll, Dieter, Nureki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035459/
https://ncbi.nlm.nih.gov/pubmed/20870747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq845
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