KSHV Reactivation from Latency Requires Pim-1 and Pim-3 Kinases to Inactivate the Latency-Associated Nuclear Antigen LANA

Host signal-transduction pathways are intimately involved in the switch between latency and productive infection of herpes viruses. As with other herpes viruses, infection by Kaposi's sarcoma herpesvirus (KSHV) displays these two phases. During latency only few viral genes are expressed, while...

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Autores principales: Cheng, Fang, Weidner-Glunde, Magdalena, Varjosalo, Markku, Rainio, Eeva-Marja, Lehtonen, Anne, Schulz, Thomas F., Koskinen, Päivi J., Taipale, Jussi, Ojala, Päivi M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648312/
https://ncbi.nlm.nih.gov/pubmed/19266083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000324
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