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A Unique SUMO-2-Interacting Motif within LANA Is Essential for KSHV Latency
Kaposi's sarcoma-associated herpesvirus (KSHV) stabilizes hypoxia-inducible factor α (HIF-1α) during latent infection, and HIF-1α reactivates lytic replication under hypoxic stress. However, the mechanism utilized by KSHV to block lytic reactivation with the accumulation of HIF-1α in latency re...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836728/ https://ncbi.nlm.nih.gov/pubmed/24278015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003750 |
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