B7-H4–deficient mice display augmented neutrophil-mediated innate immunity

B7-H4 is an immunoglobulin superfamily molecule and shown to be inhibitory for T-cell responses. To explore physiologic roles of B7-H4, we created B7-H4–deficient (KO) mice by genetic targeting. B7-H4KO mice are healthy and their T- and B-cell responses to polyclonal antigens are in normal range. Ho...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhu, Gefeng, Augustine, Mathew M., Azuma, Takeshi, Luo, Liqun, Yao, Sheng, Anand, Sudarshan, Rietz, A. Cecilia, Huang, Jiaqiang, Xu, Haiying, Flies, Andrew S., Flies, Sarah J., Tamada, Koji, Colonna, Marco, van Deursen, Jan M. A., Chen, Lieping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2009
Gaiak:
Phagocytes, Granulocytes, and Myelopoiesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647680/
https://ncbi.nlm.nih.gov/pubmed/19109567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-133223
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