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Primed innate immunity leads to autoinflammatory disease in PSTPIP2-deficient cmo mice
The mouse Lupo (I282N) mutation in proline-serine-threonine phosphatase–interacting protein 2 (PSTPIP2) leads to reduced expression of PSTPIP2 that is associated with a macrophage-mediated autoinflammatory disease. Another mutation in PSTPIP2, L98P, termed chronic multifocal osteomyelits (cmo), lead...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746474/ https://ncbi.nlm.nih.gov/pubmed/19608749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-204925 |
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