Primed innate immunity leads to autoinflammatory disease in PSTPIP2-deficient cmo mice

The mouse Lupo (I282N) mutation in proline-serine-threonine phosphatase–interacting protein 2 (PSTPIP2) leads to reduced expression of PSTPIP2 that is associated with a macrophage-mediated autoinflammatory disease. Another mutation in PSTPIP2, L98P, termed chronic multifocal osteomyelits (cmo), lead...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Chitu, Violeta, Ferguson, Polly J., de Bruijn, Rosalie, Schlueter, Annette J., Ochoa, Luis A., Waldschmidt, Thomas J., Yeung, Yee-Guide, Stanley, E. Richard
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Phagocytes, Granulocytes, and Myelopoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746474/
https://ncbi.nlm.nih.gov/pubmed/19608749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-204925
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki