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The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
PSTPIP1 is a cytoskeletal adaptor and F-BAR protein that has been implicated in autoinflammatory disease, most notably in the PAPA syndrome: pyogenic sterile arthritis, pyoderma gangrenosum, and acne. However, the mechanism by which PSTPIP1 regulates the actin cytoskeleton and contributes to disease...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3999755/ https://ncbi.nlm.nih.gov/pubmed/24421327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-516948 |
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