The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages

PSTPIP1 is a cytoskeletal adaptor and F-BAR protein that has been implicated in autoinflammatory disease, most notably in the PAPA syndrome: pyogenic sterile arthritis, pyoderma gangrenosum, and acne. However, the mechanism by which PSTPIP1 regulates the actin cytoskeleton and contributes to disease...

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Autors principals: Starnes, Taylor W., Bennin, David A., Bing, Xinyu, Eickhoff, Jens C., Grahf, Daniel C., Bellak, Jason M., Seroogy, Christine M., Ferguson, Polly J., Huttenlocher, Anna
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Phagocytes, Granulocytes, and Myelopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999755/
https://ncbi.nlm.nih.gov/pubmed/24421327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-516948
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