Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis

Tissue infiltration of phagocytes exacerbates several human pathologies including chronic inflammations or cancers. However, the mechanisms involved in macrophage migration through interstitial tissues are poorly understood. We investigated the role of Hck, a Src-family kinase involved in the organi...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Cougoule, Céline, Le Cabec, Véronique, Poincloux, Renaud, Al Saati, Talal, Mège, Jean-Louis, Tabouret, Guillaume, Lowell, Clifford A., Laviolette-Malirat, Nathalie, Maridonneau-Parini, Isabelle
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Phagocytes, Granulocytes, and Myelopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070714/
https://ncbi.nlm.nih.gov/pubmed/19897576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-218735
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