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Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis

Tissue infiltration of phagocytes exacerbates several human pathologies including chronic inflammations or cancers. However, the mechanisms involved in macrophage migration through interstitial tissues are poorly understood. We investigated the role of Hck, a Src-family kinase involved in the organi...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Cougoule, Céline, Le Cabec, Véronique, Poincloux, Renaud, Al Saati, Talal, Mège, Jean-Louis, Tabouret, Guillaume, Lowell, Clifford A., Laviolette-Malirat, Nathalie, Maridonneau-Parini, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070714/
https://ncbi.nlm.nih.gov/pubmed/19897576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-218735
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