PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts

Missense mutations that reduce or abrogate myeloid cell expression of the F-BAR domain protein, proline serine threonine phosphatase-interacting protein 2 (PSTPIP2), lead to autoinflammatory disease involving extramedullary hematopoiesis, skin and bone lesions. However, little is known about how PST...

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Detalhes bibliográficos
Main Authors: Chitu, Violeta, Nacu, Viorel, Charles, Julia F., Henne, William M., McMahon, Harvey T., Nandi, Sayan, Ketchum, Halley, Harris, Renee, Nakamura, Mary C., Stanley, E. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471520/
https://ncbi.nlm.nih.gov/pubmed/22923495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-425595
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