Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease

Macrophage actin-associated tyrosine phosphorylated protein (MAYP)/PSTPIP2, a PCH protein, is involved in the regulation of macrophage motility. Mutations in a closely related gene, PSTPIP1/CD2BP1, cause a dominantly inherited autoinflammatory disorder known as PAPA syndrome. A mutant mouse obtained...

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Detalhes bibliográficos
Main Authors: Grosse, Johannes, Chitu, Violeta, Marquardt, Andreas, Hanke, Petra, Schmittwolf, Carolin, Zeitlmann, Lutz, Schropp, Patricia, Barth, Bettina, Yu, Philipp, Paffenholz, Rainer, Stumm, Gabriele, Nehls, Michael, Stanley, E. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Phagocytes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895761/
https://ncbi.nlm.nih.gov/pubmed/16397132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3556
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