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BAR Proteins PSTPIP1/2 Regulate Podosome Dynamics and the Resorption Activity of Osteoclasts

Bone resorption in vertebrates relies on the ability of osteoclasts to assemble F-actin-rich podosomes that condense into podosomal belts, forming sealing zones. Sealing zones segregate bone-facing ruffled membranes from other membrane domains, and disassemble when osteoclasts migrate to new areas....

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Publicat a:PLoS One
Autors principals: Sztacho, Martin, Segeletz, Sandra, Sanchez-Fernandez, Maria Arantzazu, Czupalla, Cornelia, Niehage, Christian, Hoflack, Bernard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070766/
https://ncbi.nlm.nih.gov/pubmed/27760174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164829
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