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Podosome organization drives osteoclast-mediated bone resorption

Osteoclasts are the cells responsible for physiological bone resorption. A specific organization of their most prominent cytoskeletal structures, podosomes, is crucial for the degradation of mineralized bone matrix. Each podosome is constituted of an F-actin-enriched central core surrounded by a loo...

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Detalles Bibliográficos
Main Authors: Georgess, Dan, Machuca-Gayet, Irma, Blangy, Anne, Jurdic, Pierre
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198343/
https://ncbi.nlm.nih.gov/pubmed/24714644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.27840
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