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Podosome organization drives osteoclast-mediated bone resorption
Osteoclasts are the cells responsible for physiological bone resorption. A specific organization of their most prominent cytoskeletal structures, podosomes, is crucial for the degradation of mineralized bone matrix. Each podosome is constituted of an F-actin-enriched central core surrounded by a loo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198343/ https://ncbi.nlm.nih.gov/pubmed/24714644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.27840 |
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