Ładuje się......
The Stereochemistry of trans-4-Hydroxynonenal-Derived Exocyclic 1,N(2)-2′-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-Links in the 5′-CpG-3′ Sequence
[Image: see text] The trans-4-hydroxynonenal (HNE)-derived exocyclic 1,N(2)-dG adduct with (6S,8R,11S) stereochemistry forms interstrand N(2)-dG−N(2)-dG cross-links in the 5′-CpG-3′ DNA sequence context, but the corresponding adduct possessing (6R,8S,11R) stereochemistry does not. Both exist primari...
Zapisane w:
| Główni autorzy: | , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical Society
2008
|
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646759/ https://ncbi.nlm.nih.gov/pubmed/18847226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8011143 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|