Vitamin D Deficiency Modulates Graves’ Hyperthyroidism Induced in BALB/c Mice by Thyrotropin Receptor Immunization

TSH receptor (TSHR) antibodies and hyperthyroidism are induced by immunizing mice with adenovirus encoding the TSHR or its A-subunit. Depleting regulatory T cells (Treg) exacerbates thyrotoxicosis in susceptible BALB/c mice and induces hyperthyroidism in normally resistant C57BL/6 mice. Vitamin D pl...

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Bibliographische Detailangaben
Hauptverfasser: Misharin, Alexander, Hewison, Martin, Chen, Chun-Rong, Lagishetty, Venu, Aliesky, Holly A., Mizutori, Yumiko, Rapoport, Basil, McLachlan, Sandra M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Endocrine Society 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646531/
https://ncbi.nlm.nih.gov/pubmed/18927213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1191
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