Single-step High-yield Radiosynthesis and Evaluation of a Sensitive (18)F-Labeled Ligand for Imaging Brain Peripheral Benzodiazepine Receptors with PET

Elevated levels of peripheral benzodiazepine receptors (PBR) are associated with activated microglia in their response to inflammation. Hence, PBR imaging in vivo is valuable for investigating brain inflammatory conditions. Sensitive, easily prepared and readily available radioligands for imaging wi...

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Hlavní autoři: Briard, Emmanuelle, Zoghbi, Sami S., Siméon, Fabrice G., Imaizumi, Masao, Gourley, Jonathan P., Shetty, H. Umesha, Lu, Shuiyu, Fujita, Masahiro, Innis, Robert B., Pike, Victor W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646257/
https://ncbi.nlm.nih.gov/pubmed/19119848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8011855
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