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Single-step High-yield Radiosynthesis and Evaluation of a Sensitive (18)F-Labeled Ligand for Imaging Brain Peripheral Benzodiazepine Receptors with PET
Elevated levels of peripheral benzodiazepine receptors (PBR) are associated with activated microglia in their response to inflammation. Hence, PBR imaging in vivo is valuable for investigating brain inflammatory conditions. Sensitive, easily prepared and readily available radioligands for imaging wi...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646257/ https://ncbi.nlm.nih.gov/pubmed/19119848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8011855 |
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