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Vaccinia Virus-Mediated Inhibition of Type I Interferon Responses Is a Multifactorial Process Involving the Soluble Type I Interferon Receptor B18 and Intracellular Components

Poxviruses such as virulent vaccinia virus (VACV) strain Western Reserve encode a broad range of immune modulators that interfere with host responses to infection. Upon more than 570 in vitro passages in chicken embryo fibroblasts (CEF), chorioallantois VACV Ankara (CVA) accumulated mutations that r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Waibler, Zoe, Anzaghe, Martina, Frenz, Theresa, Schwantes, Astrid, Pöhlmann, Christopher, Ludwig, Holger, Palomo-Otero, Marcos, Alcamí, Antonio, Sutter, Gerd, Kalinke, Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643777/
https://ncbi.nlm.nih.gov/pubmed/19073732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01617-08
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