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In Vivo Conditions Enable IFNAR-Independent Type I Interferon Production by Peritoneal CD11b(+) Cells upon Thogoto Virus Infection

Type I interferons (IFNs) crucially contribute to host survival upon viral infections. Robust expression of type I IFNs (IFN-α/β) and induction of an antiviral state critically depend on amplification of the IFN signal via the type I IFN receptor (IFNAR). A small amount of type I IFN produced early...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kochs, Georg, Anzaghe, Martina, Kronhart, Stefanie, Wagner, Valentina, Gogesch, Patricia, Scheu, Stefanie, Lienenklaus, Stefan, Waibler, Zoe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044850/
https://ncbi.nlm.nih.gov/pubmed/27512061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00744-16
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