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Thogoto Virus Infection Induces Sustained Type I Interferon Responses That Depend on RIG-I-Like Helicase Signaling of Conventional Dendritic Cells

Type I interferon (IFN-α/β) induction upon viral infection contributes to the early antiviral host defense and ensures survival until the onset of adaptive immunity. Many viral infections lead to an acute, transient IFN expression which peaks a few hours after infection and reverts to initial levels...

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Detalhes bibliográficos
Main Authors: Kochs, Georg, Bauer, Stefanie, Vogt, Carola, Frenz, Theresa, Tschopp, Jürg, Kalinke, Ulrich, Waibler, Zoe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976394/
https://ncbi.nlm.nih.gov/pubmed/20861272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00931-10
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