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Thogoto Virus Infection Induces Sustained Type I Interferon Responses That Depend on RIG-I-Like Helicase Signaling of Conventional Dendritic Cells

Type I interferon (IFN-α/β) induction upon viral infection contributes to the early antiviral host defense and ensures survival until the onset of adaptive immunity. Many viral infections lead to an acute, transient IFN expression which peaks a few hours after infection and reverts to initial levels...

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Hlavní autoři: Kochs, Georg, Bauer, Stefanie, Vogt, Carola, Frenz, Theresa, Tschopp, Jürg, Kalinke, Ulrich, Waibler, Zoe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976394/
https://ncbi.nlm.nih.gov/pubmed/20861272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00931-10
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