Rapid Expansion of CD8(+) T Cells in Wild-Type and Type I Interferon Receptor-Deficient Mice Correlates with Protection after Low-Dose Emergency Immunization with Modified Vaccinia Virus Ankara

Immunization with modified vaccinia virus Ankara (MVA) can rapidly protect mice against lethal ectromelia virus (ECTV) infection, serving as an experimental model for severe systemic infections. Importantly, this early protective capacity of MVA vaccination completely depends on virus-specific cytot...

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Detalhes bibliográficos
Main Authors: Volz, Asisa, Langenmayer, Martin, Jany, Sylvia, Kalinke, Ulrich, Sutter, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178859/
https://ncbi.nlm.nih.gov/pubmed/25008931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00945-14
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