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Rapid Expansion of CD8(+) T Cells in Wild-Type and Type I Interferon Receptor-Deficient Mice Correlates with Protection after Low-Dose Emergency Immunization with Modified Vaccinia Virus Ankara

Immunization with modified vaccinia virus Ankara (MVA) can rapidly protect mice against lethal ectromelia virus (ECTV) infection, serving as an experimental model for severe systemic infections. Importantly, this early protective capacity of MVA vaccination completely depends on virus-specific cytot...

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Main Authors: Volz, Asisa, Langenmayer, Martin, Jany, Sylvia, Kalinke, Ulrich, Sutter, Gerd
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178859/
https://ncbi.nlm.nih.gov/pubmed/25008931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00945-14
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