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Modified Vaccinia Virus Ankara Induces Toll-Like Receptor-Independent Type I Interferon Responses

Modified vaccinia virus Ankara (MVA) is a highly attenuated vaccinia virus strain undergoing clinical evaluation as a replication-deficient vaccine vector against various infections and tumor diseases. To analyze the basis of its high immunogenicity, we investigated the mechanism of how MVA induces...

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Detalhes bibliográficos
Main Authors: Waibler, Zoe, Anzaghe, Martina, Ludwig, Holger, Akira, Shizuo, Weiss, Siegfried, Sutter, Gerd, Kalinke, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168990/
https://ncbi.nlm.nih.gov/pubmed/17855554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01190-07
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