Interleukin-1β receptor expressed by modified vaccinia virus Ankara interferes with interleukin-1β activity produced in various virus-infected antigen-presenting cells

BACKGROUND: Modified vaccinia virus Ankara (MVA) is a highly attenuated virus and a promising vaccine vector with potent immune stimulating properties. Deletion of the gene encoding the viral interleukin-1beta receptor (vIL-1βR) in MVA (MVAΔIL-1βR) was previously shown to enhance memory T cell funct...

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Bibliographic Details
Main Authors: Zimmerling, Stefan, Waibler, Zoe, Resch, Theresa, Sutter, Gerd, Schwantes, Astrid
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616829/
https://ncbi.nlm.nih.gov/pubmed/23356675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-34
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