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The Orthopoxvirus 68-Kilodalton Ankyrin-Like Protein Is Essential for DNA Replication and Complete Gene Expression of Modified Vaccinia Virus Ankara in Nonpermissive Human and Murine Cells

Modified vaccinia virus Ankara (MVA) is a highly attenuated and replication-deficient vaccinia virus (VACV) that is being evaluated as replacement smallpox vaccine and candidate viral vector. MVA lacks many genes associated with virulence and/or regulation of virus tropism. The 68-kDa ankyrin-like p...

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Detalhes bibliográficos
Main Authors: Sperling, Karin M., Schwantes, Astrid, Staib, Caroline, Schnierle, Barbara S., Sutter, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687370/
https://ncbi.nlm.nih.gov/pubmed/19357172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01628-08
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