Gamma Interferon-Induced Interferon Regulatory Factor 1-Dependent Antiviral Response Inhibits Vaccinia Virus Replication in Mouse but Not Human Fibroblasts

Vaccinia virus (VACV) replicates in mouse and human fibroblasts with comparable kinetics and efficiency, yielding similar titers of infectious progeny. Here we demonstrate that gamma interferon (IFN-γ) but not IFN-α or IFN-β pretreatment of mouse fibroblasts prior to VACV infection induces a long-la...

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Detalhes bibliográficos
Main Authors: Trilling, Mirko, Le, Vu Thuy Khanh, Zimmermann, Albert, Ludwig, Holger, Pfeffer, Klaus, Sutter, Gerd, Smith, Geoffrey L., Hengel, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663247/
https://ncbi.nlm.nih.gov/pubmed/19211768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02042-08
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