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Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins

MicroRNAs (miRNAs) repress target genes through a poorly defined antisense mechanism. Cell-free and cell-based assays have supported the idea that miRNAs repress their target mRNAs by blocking initiation of translation, whereas studies in animal models argued against this possibility. We examined en...

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Detaylı Bibliyografya
Asıl Yazarlar: Ding, Xavier C, Großhans, Helge
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637332/
https://ncbi.nlm.nih.gov/pubmed/19131968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.275
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