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The let-7 microRNA interfaces extensively with the translation machinery to regulate cell differentiation

MicroRNAs (miRNAs) are noncoding RNAs that regulate numerous target genes through a posttranscriptional mechanism and thus control major developmental pathways. The phylogenetically conserved let-7 miRNA regulates cell proliferation and differentiation, thus functioning as a key regulator of develop...

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Detalhes bibliográficos
Main Authors: Ding, Xavier C., Slack, Frank J., Großhans, Helge
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887667/
https://ncbi.nlm.nih.gov/pubmed/18818519
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